Intrinsic Therapeutics, Inc. is a commercial-stage company marketing an implant designed to reconstruct herniated lumbar discs. Intrinsic’s proprietary Barricaid® anular prosthesis is a barrier that securely closes ruptures in the anulus fibrosus, the outer structure of the disc. These ruptures lead to disc herniations, sciatica, and low back pain and result in over 1,000,000 surgical procedures annually. These commonly-performed discectomy procedures have been documented to result in clinical failure for in 10-12% of all patients, a remarkable statistic given the frequency of this procedure worldwide.